IMMUNO-COV™

Test overview

What does the test measure?

Measures your blood level of protective antibodies that can inactivate the viruses causing COVID-19

What is the test used for? How does it relate to one’s health?

  • Helps determine your risk of catching or becoming sick from COVID-19.
  • Measures the most important indicator of protection against COVID-19 in people who have been vaccinated or have recovered from a suspected SARS-CoV-2 infection. 
  • You can use the test result to guide your personal decisions on social distancing, travel, attending large gatherings, what to do if you get symptoms that could indicate COVID-19 and whether you should get a booster shot of the vaccine.

Who should get tested?

Testing can be beneficial for anyone who has been vaccinated or was previously infected if they believe they may be at higher risk of serious or fatal COVID-19, and for those who live with or care for people at higher risk, such as:

  • People with a suppressed immune system due to previous organ transplantation, blood cancer, inherited immune deficiencies and/or who are receiving immune suppressive drug therapy
  • People with increased vulnerability due to advanced age and associated chronic health conditions
  • People who travel extensively for work and who have regular contact with others who travel and socialize
  • People who are planning to attend a large gathering (such as a wedding) where social distancing measures are not planned.

How do I get tested?

The IMMUNO-COV test is available as a physician ordered test and requires a blood draw. You can ask your physician to order it using the instructions here.

Results Information

What results may mean

The test tells you the amount of neutralizing antibodies that can block the infection of the virus that causes COVID19.  The results help you to understand if your antibody titer (level in your blood) is or is not sufficient to protect you from mild and/or severe COVID-19 illness caused by different (variant) strains of SARS-CoV-2.

A very low or undetectable antibody titer indicates a low level of protection, hence the need to consider a booster vaccination

Treatment or follow up 

You should speak with your physician regarding the interpretation of your test results.

Testing Process

Risks involved 

There is a very low risk involved in giving a regular blood sample for this test or finger stick.

How to prepare for the test

No preparation is required. You can give your blood sample at any time of day.

SARS-CoV-2 neutralizing antibody titer

The IMMUNO-COV test measures the titer (level) of protective COVID-19 neutralizing antibodies in your blood. The test result can help you assess your risk of getting sick if you come into contact with the virus that causes COVID-19.

Who should get tested?

Testing can provide helpful information for anyone who believes they may be at higher risk of serious or fatal COVID-19, and for those who live with or care for people at higher risk. This includes (i) people with a suppressed immune system due to previous organ transplantation, blood cancer, inherited immune deficiencies and/or who are receiving immune suppressive drug therapy; (ii) people with increased vulnerability due to advanced age and associated chronic health conditions. The information may also be useful for people who travel extensively for work and who have regular contact with others who travel and socialize or people who are planning to attend a large gathering (such as a wedding) where social distancing measures are not planned.

What will my test results tell me?

Your test will tell you your titer (blood level) of protective neutralizing antibodies against the virus that causes COVID-19.  You should speak with your physician regarding the interpretation of your test results. Read more about how neutralizing antibody titers relate to protection and immunity against COVID19 here .

Are there any risks involved in getting this test?

There is minimal risk involved in giving a regular blood sample at the lab or a finger stick.

Khoury, D.S. et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med 27, 1205–1211 (2021). https://doi.org/10.1038/s41591-021-01377-8; 

Feng S. et al. Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection, medRxiv 2021.06.21.21258528; doi: https://doi.org/10.1101/2021.06.21.21258528, 

Gilbert et al., Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy trial, medRxiv 2021.08.09.21261290; doi: https://doi.org/10.1101/2021.08.09.21261290

Planas et al. Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. Nature, VOL 596, pages 276-282. https://www.nature.com/articles/s41586-021-03777-9.pdf

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